The Centre for Stem Cell Biology (CSCB) complements the existing strengths in developmental biology at the University of Sheffield. We provide a focus on the development of human ES cell technologies and resources that are central to the long-term goal of developing clinical applications of stem cells in regenerative medicine.

The Centre has extensive experience in the culture, characterisation and biology of human embryonic stem (ES) cells and their malignant counterpart embryonal carcinoma (EC) cells. It has access to a range of immunological and molecular markers and long-standing experience in their application to the characterisation and identification of stem cell lines. We have expertise in proteomics and other molecular techniques as well as methodologies for manipulating gene expression in these cells, and are recognised for its development and application of RNA interference techniques.

The Centre represents a significant opportunity for collaborative activity with all organisations involved in stem cell research and allied technology development over a wide range of activities. The CSCB has a particularly long-standing experience in collaborative research with business & industry and the Centre is currently expanding its research capacity through the development of new GMP accredited laboratories for the production of human ES cells.

From the highly focused academic research programme of the Centre itself, to it’s collaborative industrial partnerships and stem cell training activities the Centre for Stem Cell Biology is able to offer a wide range of opportunities to both academia and business & industry.